Medical Device

The Problem

Inhaled nitric oxide (iNO) is a critical therapeutic gas with vasodilatory, anti-inflammatory, and antimicrobial properties, used to treat life-threatening conditions like pulmonary hypertension.

Current delivery systems are complex, costly, and restricted to major medical centers. They rely on highly diluted NO in nitrogen, require specialized scrubbers for toxic NO₂, frequent consumable changes, and large, non-portable equipment—limiting broader adoption and increasing care complexity.

Venous thromboembolism (VTE)—including deep vein thrombosis (DVT) and pulmonary embolism (PE)—remains a leading cause of morbidity and mortality worldwide.

Current standards of care have significant limitations:

In hospitals and private practices, patient photos are essential for documentation, diagnosis, and outcomes tracking — yet most providers still use unsecured smartphone cameras and inconsistent processes.

This leads to HIPAA violations, lost or misfileed images, and inconsistent before-and-after documentation that diminishes clinical and marketing value.

TPM Research is addressing a long-standing gap in hospital patient care: the transition from bed to chair, lab, bathroom, or vehicle.

For nearly 90 years, the standard solution has been the traditional collapsible wheelchair with its well-known limitations. The Care Continuum Chair changes that with innovative features that deliver superior clinical, aesthetic, and financial outcomes.

InTailor Bariatrics is advancing endoscopic automatic gastroplasty—an innovative technology that automates tissue acquisition, configuration, and fixation for consistent, reproducible outcomes and widespread physician adoption.

SYMBIO-X Health is a Vanderbilt spin-out developing the first hardware-firmware co-designed wearable that delivers Doppler-grade cardiac valve metrics continuously at home—eliminating dependence on facility-based echo/MRI.

Every year, preventable deaths occur due to gaps in human monitoring—officers can’t watch every cell, and caregivers can’t reach every room. Traditional solutions rely on wearables, invasive cameras, or manual checks that compromise privacy or fail when devices are forgotten or refused.

Rahm Sensor Development addresses this critical need with contact-free radar, thermal, and intelligent video fusion processed entirely on-device.

ThorafiX addresses Proximal Junctional Kyphosis (PJK), a debilitating complication affecting up to 46% of adult spinal deformity cases. PJK causes structural breakdown at the top of long spinal fusions, leading to vertebral collapse, severe pain, and costly revision surgeries.

Current approaches—pedicle screw-only constructs or soft-tissue preservation—fail to provide lasting biomechanical protection.

Tricuspid regurgitation (TR) is the most common valvular heart disease, affecting more than 20 million people in the US, including 1.8 million with severe dysfunction.

TR occurs when the tricuspid valve fails to close properly, allowing blood to flow backward from the right ventricle to the right atrium. As severity increases, the heart works harder, leading to reduced quality of life, end-organ dysfunction, and higher mortality.

Imagine Devices Inc. is revolutionizing neonatal and pediatric critical care with a safer, smarter approach to monitoring premature infants.

Each year, over 13 million premature infants are admitted to Neonatal Intensive Care Units (NICUs) worldwide, connected to more than 20 wires, tubes, and sensors for feeding, respiratory support, and vital signs. Conventional systems create serious risks—including nasal and skin injuries, infections, respiratory complications, and high clinical workload.